Photosensitized conjugate addition
Photochemistry in continuous flow offers multiple advantages over its batch-wise analogue. Photochemical reactions are driven by the amount of photons being able to reach reactive molecules causing the activation and thus the desired reaction. In order to enhance reaction rate, the area of the reactor being reached by the light source can be increased. Using a microreactor, this can be achieved in a convenient way. We offer different solutions for different wavelengths: for wavelengths down to 365 nm, LED light sources can be used. For lower wavelengths, no LED lightsources are available which are powerful enough, so for those applications conventional mercury lamp set ups are available.
A model reaction – the photosensitized conjugate addition of isopropanol to furanone – was successfully translated from batch to continuous flow in the FlowStart Evo microreactor platform expanded with the Photochemistry module, showing the viability of continuous flow photochemistry. Interested in the full application note please contact us